Champions League Round of 16: Key Matchups and Predictions

The 2025 UEFA Champions League Round of 16 draw has set the stage for some of the most exciting clashes in European football. Here’s a detailed look at the key matchups and our predictions for each tie.

Paris Saint-Germain vs. Liverpool

This is undoubtedly one of the most anticipated ties of the round. Liverpool, who topped their group with an impressive record of seven wins and one defeat, face a resurgent PSG side that has found form in recent weeks. PSG’s talismanic winger Ousmane Dembélé and the recent addition of Khvicha Kvaratskhelia make them a formidable opponent. While Liverpool are the favorites, PSG’s pace and confidence could see them edge this tightly contested matchup.

Prediction: PSG to advance.

Real Madrid vs. Atletico Madrid

The Madrid derby is set to add another chapter to its storied history in the Champions League. Real Madrid, buoyed by Kylian Mbappé’s heroics in the previous round, will look to continue their dominance over Atletico. However, Diego Simeone’s side has shown resilience in La Liga this season, and with the second leg at home, they might just have what it takes to turn the tide.

Prediction: Real Madrid to advance.

Bayern Munich vs. Bayer Leverkusen

A clash of titans in German football, this tie pits six-time European champions Bayern Munich against the reigning Bundesliga champions, Bayer Leverkusen. With the Allianz Arena hosting this year’s final, Bayern will be desperate to overcome their domestic rivals. However, Xabi Alonso’s Leverkusen has been in fine form and could spring a surprise, especially with questions over Harry Kane’s fitness.

Prediction: Bayer Leverkusen to advance.

Benfica vs. Barcelona

Expect a goal-fest in this encounter. Barcelona’s attacking trio of Robert Lewandowski, Lamine Yamal, and Raphinha is one of the best in Europe, and they will be looking to overpower Benfica. However, with Vangelis Pavlidis in fine form, Benfica could make this a thrilling contest.

Prediction: Barcelona to advance.

Borussia Dortmund vs. Lille

Borussia Dortmund, under new coach Niko Kovac, face a Lille side that has been inconsistent in Ligue 1. With Serhou Guirassy in red-hot form, Dortmund will be confident of advancing. Lille’s Jonathan David and Osame Sahraoui, however, could make this a close tie.

Prediction: Borussia Dortmund to advance.

Feyenoord vs. Inter Milan

Robin van Persie’s Feyenoord face a tough challenge against Inter Milan, who boast the best defensive record in the competition. With Lautaro Martínez and Marcus Thuram leading the line, Inter will be hard to beat, especially with their experience in knockout football.

Prediction: Inter Milan to advance.

Conclusion

The Round of 16 promises high drama and unforgettable moments, with every team fighting for a place in the quarterfinals. Stay tuned as we count down to the first leg of these exciting matches.