2025 Big Ten Football Betting Guide: Ohio State Buckeyes and Key Conference Insights
Explore the 2025 Big Ten football season with a focus on Ohio State Buckeyes' potential, key betting insights, and team analysis for top contenders.

Ohio State Buckeyes: A Season of High Expectations
The Ohio State Buckeyes enter the 2025 season as the defending national champions, poised for another strong run. With a roster brimming with talent, the Buckeyes are led by quarterback Julian Sayin, a former five-star recruit ready to make his mark. The team boasts one of the best defenses in college football, anchored by safety Caleb Downs and linebacker Sonny Styles.
Key Strengths
- Defensive Dominance: The Buckeyes' defense is expected to be a cornerstone of their success, with a front seven capable of pressuring quarterbacks and limiting big plays.
- Offensive Firepower: Julian Sayin steps into the starting role with a wealth of talent around him, including a deep receiving corps featuring Jeremiah Smith, Carnell Tate, and Brandon Inniss.
Potential Challenges
- Inexperience at QB: Sayin’s first career start comes against No. 1 Texas, a tough test for any rookie quarterback.
- New Playcallers: With Brian Hartline and Matt Patricia taking over offensive and defensive playcalling, respectively, there could be an adjustment period.
Betting Insights
Ohio State OVER 10.5 Wins (+115)
Despite the challenges, the Buckeyes have a favorable schedule with key games at home, including matchups against Michigan and Penn State. With elite talent and a strong defense, Ohio State is well-positioned to surpass the 10.5-win mark.
Other Big Ten Bets
- Iowa OVER 7.5 Wins (+120): With an upgraded quarterback in Mark Gronowski, Iowa’s offense looks more dynamic, making the over a solid bet.
- Nebraska UNDER 7.5 Wins (+125): Despite the optimism surrounding Matt Rhule’s third year, Nebraska’s struggles in close games could hinder their progress.
- Penn State OVER 10.5 Wins (+105): Penn State’s completeness on paper makes them a strong candidate to exceed expectations, though the margin for error is slim.
- Michigan to MAKE the CFP (+200): With a talented roster and momentum from last season, Michigan is a dark horse to return to the College Football Playoff.
Conclusion
The 2025 Big Ten season promises to be one of transformation and high stakes. Ohio State, with its balanced roster and championship pedigree, is a team to watch. Betting on the Buckeyes to exceed their win total offers solid value, while other teams like Iowa and Penn State present intriguing opportunities for bettors.