NFL Week 2 2025: Expert Predictions, Key Matchups, and Game Previews

Get ready for NFL Week 2 with expert predictions, in-depth game previews, and key insights into the most exciting matchups of the 2025 season.

NFL Week 2 2025: Game Previews and Predictions

The second week of the 2025 NFL season is packed with thrilling matchups, including some high-stakes rematches and intriguing storylines. Here’s a breakdown of what to expect:

Lions vs. Bears: A Homecoming for Ben Johnson

The Lions will face their former offensive coordinator, Ben Johnson, now with the Bears. Detroit is looking to avoid an 0-2 start, while Chicago aims to improve their offensive consistency.

  • Key Stat: Jared Goff is chasing history, aiming to win 11 straight games after a loss.
  • Bold Prediction: The Bears will record at least three 30-plus-yard plays.

Bills vs. Jets: AFC East Showdown

The Bills and Jets clash in a divisional rivalry. Buffalo’s defense will be tested against a rejuvenated Jets offense that put up 32 points in Week 1.

  • Key Stat: Josh Allen has 18 career turnovers against the Jets.
  • Bold Prediction: Jets CB Brandon Stephens will be targeted at least nine times.

Ravens vs. Browns: Battle in the AFC North

The Ravens, led by Lamar Jackson, face a tough Browns defense. Cleveland will need to contain Derrick Henry to have a chance.

  • Key Stat: The Ravens are 12-2 following a loss since 2022.
  • Bold Prediction: Mark Andrews will bounce back with five receptions and a TD.

Chiefs vs. Eagles: Super Bowl Rematch

A highly anticipated rematch of Super Bowl LIX, the Chiefs and Eagles will battle it out in Kansas City. Both teams are looking to make an early statement.

  • Key Stat: This is the fourth Super Bowl rematch in Week 1 or 2.
  • Bold Prediction: Eagles’ Joshua Uche will force a critical Mahomes mistake.

Other Notable Matchups:

  • Jaguars vs. Bengals: Joe Burrow faces Trevor Lawrence in a battle of former college stars.
  • Seahawks vs. Steelers: Both teams look to rebound after Week 1 struggles.
  • 49ers vs. Saints: San Francisco aims to overcome injuries to key players.

Expert Picks and Predictions

Our analysts have weighed in with their final score predictions for every game. Here’s a quick look:

  • Lions vs. Bears: Analysts are split, but the Lions are favored.
  • Bills vs. Jets: Buffalo is expected to edge out the Jets.
  • Ravens vs. Browns: Baltimore is heavily favored to win.
  • Chiefs vs. Eagles: A close game, but the Eagles are slightly favored.

Fantasy and Betting Insights

  • Fantasy Nugget: Keep an eye on Travis Etienne Jr. against the Bengals’ defense.
  • Betting Nugget: The Bills have covered three straight meetings against the Jets.

Conclusion

Week 2 of the 2025 NFL season promises to deliver excitement, drama, and plenty of action. Whether you’re a fan, fantasy manager, or bettor, these games are not to be missed!

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